Adapted for use across diverse chemical handling environments, the Hplc Column Nucleodur® C 18 Isis offers exceptional versatility in liquid chromatography applications. With its unique nonpolar crosslinked polymeric octadecyl (C 18, ODS) modification, this UHPLC column delivers high steric selectivity, making it ideal for separating positional and structural isomers, planar/non-planar molecules, and even steroids. Its recommended applications extend to fat-soluble vitamins and suitable LC-MS uses, particularly for (o,p,m)-substituted aromatics. The column's pressure stability of up to 900 bar ensures robust performance under various conditions, while its temperature stability of 60°C further enhances its adaptability.

• Category: Separation columns for HPLC
• Specific surface according to BET: 340 m²/g
• USP listing: L1
• Endcapped: yes
• Particle type: Fully porous particles (FPP)
• Interactions / retention mechanism: steric and hydrophobic
• Pore size: 110 Å
• Phase: C 18 Isis
• Pressure stability: 900 bar
• pH stability: 1,0-10,0
• Recommended application(s): Separation of positional and structural isomers Planar/non-planar molecules Steroids Suitable for LC-MS (o,p,m-)Substituted aromatics Fat-soluble vitamins Exceptional steric selectivity
• L x Ø internal (column): 50 x 3 mm
• Separation principle: Reversed phase (RP)
• Particle size: 1.8 µm
• Column volume: 0.35 ml
• Column type: UHPLC column
• Column shape: Analytical separation column
• Temperature stability: 60 ° C
• Surface chemistry: Nonpolar crosslinked polymeric octadecyl (C 18 , ODS) modification, High steric selectivity
• Pore volume: 0.9 ml/g
• Eluent in column: Acetonitrile - Water
• Application Database (Macherey-Nagel): HPLC