Intended for structured formulation workflows, the Hplc Column Nucleodur® C 18 Gravity SB offers exceptional versatility within the realm of separation columns for HPLC. Featuring a C 18 Gravity SB phase, this column exhibits distinct polar selectivity, ensuring superior retention of early eluting substances. Crafted from high purity NUCLEODUR® silica gel, it demonstrates outstanding performance under highly aqueous conditions, making it particularly suited for LC/MS applications. Its base deactivated (BDS), high density octadecyl (C 18, ODS) modification ensures hydrophobic (van der Waals) interactions with additional polar interactions, ideal for overall sophisticated analytical separations, especially for polar compounds such as antibiotics, organic acids, water-soluble vitamins, and more.

• Category: Separation columns for HPLC
• Interactions / retention mechanism: hydrophobic (van der Waals) with additional polar interactions
• Specific surface according to BET: 340 m²/g
• Endcapped: yes
• Pressure stability: 600 bar
• Column type: HPLC column
• Pore volume: 0.9 ml/g
• Phase: C 18 Gravity SB
• USP listing: L1
• pH stability: 1,0-9,0
• Column shape: Analytical separation column
• Particle type: Fully porous particles (FPP)
• Recommended application(s): Overall sophisticated analytical separations Antibiotics Organic acids Ideal for method development Especially for polar compounds Water soluble vitamins Excellent performance under highly aqueous conditions
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• L x Ø internal (column): 250 x 2 mm
• Pore size: 110 Å
• Column volume: 0.8 ml
• Temperature stability: 60 ° C
• Particle size: 5 µm