Built to deliver predictable results in synthesis routines, the Separation columns for HPLC category includes the HPLC column NUCLEODUR ® C 18 Gravity, 5 μm, 250 mm, 3 mm. This column features a high density C 18 phase based on high purity NUCLEODUR ® silica gel, endcapped to suppress unwanted polar interactions between the silica surface and the sample. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it an ideal choice for method development and valuable for RP applications. With a recommended application range including basic pharmaceuticals, antidepressants, anti-inflammatory drugs, and herbicides, this column is a versatile tool for various synthetic processes.

• Category: Separation columns for HPLC
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Pore size: 110 Å
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Temperature stability: 60 ° C
• Column type: HPLC column
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• Eluent in column: Acetonitrile - Water
• USP listing: L1
• Phase: C 18 Gravity
• Column shape: Analytical separation column
• Pore volume: 0.9 ml/g
• Application Database (Macherey-Nagel): HPLC
• Particle size: 5 µm
• pH stability: 1,0-11,0
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• L x Ø internal (column): 250 x 3 mm
• Pressure stability: 600 bar
• Column volume: 1.75 ml
• Endcapped: yes