Produced for stability across temperature-sensitive applications, this Separation column for HPLC, specifically the HPLC column NUCLEODUR ® C 18 Gravity, boasts a high density C 18 phase based on high purity NUCLEODUR ® silica gel. Its endcapping feature suppresses unwanted polar interactions, making it ideal for separating basic and other ionizable analytes. With enhanced pH stability, LC/MS suitability, and superior base deactivation, it's an excellent choice for method development and valuable for RP applications. It features a particle size of 1.8 μm, a specific surface area of 340 m²/g, and a recommended application range including pharmaceuticals, herbicides, and anti-inflammatory drugs.

• Category: Separation columns for HPLC
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Pore volume: 0.9 ml/g
• Endcapped: yes
• Column volume: 0.1 ml
• Pressure stability: 900 bar
• Pore size: 110 Å
• Separation principle: Reversed phase (RP)
• Particle type: Fully porous particles (FPP)
• USP listing: L1
• Eluent in column: Acetonitrile - Water
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Specific surface according to BET: 340 m²/g
• L x Ø internal (column): 30 x 2 mm
• Particle size: 1.8 µm
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Column shape: Analytical separation column
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Column type: UHPLC column
• Phase: C 18 Gravity
• pH stability: 1,0-11,0
• Temperature stability: 60 ° C