HPLC column NUCLEODUR ® C 18 Pyramid, 3 µm, 100 mm, 3 mm

Recommended for applications requiring controlled solvent behavior, such as pharmaceutical raw material separations, the HPLC Column Nucleodur® C 18 Pyramid offers superior performance with its fully porous particles (FPP). With a particle size of 3 μm and a pore size of 110 Å, it provides a specific surface area of 340 m²/g according to BET. This column's unique feature is its polar endcapping, making it suitable for aqueous eluents, often referred to as an “aqua column.” It exhibits hydrophobic and polar interactions (H bonds), ensuring efficient retention of very polar compounds like organic acids, penicillin antibiotics, and nucleic acid bases. The column's temperature stability up to 60°C and pressure resistance up to 600 bar make it ideal for various

• Category: Separation columns for HPLC
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Separation principle: Reversed phase (RP)
• Particle size: 3 µm
• Column shape: Analytical separation column
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Pressure stability: 600 bar
• L x Ø internal (column): 100 x 3 mm
• USP listing: L1
• pH stability: 1,0-9,0
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Endcapped: yes
• Temperature stability: 60 ° C
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Pore size: 110 Å
• Pore volume: 0.9 ml/g
• Eluent in column: Acetonitrile - Water
• Particle type: Fully porous particles (FPP)
• Phase: C 18 Pyramid
• Column type: HPLC column
• Specific surface according to BET: 340 m²/g
• Column volume: 0.7 ml