Configured for stable performance in synthesis settings, the HPLC Column Nucleodur® C 8 Gravity, 1.8 μm, 100 mm, 3 mm offers exceptional versatility due to its reversed phase (RP) separation principle. With a particle size of 1.8 μm, this UHPLC column delivers high efficiency and rapid separations. Its high density C 8 phase, based on high purity NUCLEODUR® silica gel, ensures minimal unwanted polar interactions, making it ideal for the separation of basic and other ionizable analytes. Additionally, the column's enhanced pH stability, LC/MS suitability, and superior base deactivation make it an excellent choice for method development and valuable for RP applications.

• Category: Separation columns for HPLC
• Column shape: Analytical separation column
• Separation principle: Reversed phase (RP)
• Column type: UHPLC column
• L x Ø internal (column): 100 x 3 mm
• Pore size: 110 Å
• Pressure stability: 900 bar
• Endcapped: yes
• Specific surface according to BET: 340 m²/g
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• pH stability: 1,0-11,0
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Temperature stability: 60 ° C
• Phase: C 8 Gravity
• Particle type: Fully porous particles (FPP)
• Particle size: 1.8 µm
• Column volume: 0.7 ml
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Eluent in column: Acetonitrile - Water
• Pore volume: 0.9 ml/g
• USP listing: L7