Developed for demanding processing applications, the Hplc Column Nucleodur® C 18 Pyramid, 1.8 μm, 100 mm, 2 mm offers superior performance in separating very polar compounds such as pharmaceutical raw materials, analgesics, and water-soluble vitamins. Its unique polar endcapping makes it suitable for aqueous eluents, earning it the nickname "aqua column". With a pore size of 110 Å and a specific surface area of 340 m²/g, this UHPLC column provides exceptional efficiency and resolution. It features fully porous particles (FPP), ensuring high pressure stability up to 900 bar and temperature stability up to 60°C. Recommended applications include complexing agents, nucleic acid bases, organic acids, penicillin antibiotics

• Category: Separation columns for HPLC
• Particle size: 1.8 µm
• Column shape: Analytical separation column
• Temperature stability: 60 ° C
• Pore size: 110 Å
• Phase: C 18 Pyramid
• USP listing: L1
• Application Database (Macherey-Nagel): HPLC
• Pore volume: 0.9 ml/g
• Column volume: 0.3 ml
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Pressure stability: 900 bar
• pH stability: 1,0-9,0
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Endcapped: yes
• Column type: UHPLC column
• Separation principle: Reversed phase (RP)
• Particle type: Fully porous particles (FPP)
• Eluent in column: Acetonitrile - Water
• L x Ø internal (column): 100 x 2 mm
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Specific surface according to BET: 340 m²/g
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping