Engineered to maintain reliability in process-driven workflows, the HPLC column NUCLEODUR ® C 18 Gravity, 3 μm, 100 mm, 4 mm, falls under the category of separation columns for HPLC. Featuring a high density C 18 phase based on high purity NUCLEODUR ® silica gel, this column suppresses unwanted polar interactions between the silica surface and the sample, making it ideal for the separation of basic and other ionizable analytes. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it a perfect choice for method development and valuable for RP applications.

• Category: Separation columns for HPLC
• USP listing: L1
• Eluent in column: Acetonitrile - Water
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Phase: C 18 Gravity
• Separation principle: Reversed phase (RP)
• Specific surface according to BET: 340 m²/g
• Particle size: 3 µm
• L x Ø internal (column): 100 x 4 mm
• Endcapped: yes
• Pressure stability: 600 bar
• Particle type: Fully porous particles (FPP)
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Temperature stability: 60 ° C
• pH stability: 1,0-11,0
• Column shape: Analytical separation column
• Column type: HPLC column
• Column volume: 1.25 ml
• Pore size: 110 Å
• Pore volume: 0.9 ml/g
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification