Designed for professional use, the Separation columns for HPLC include the HPLC column NUCLEODUR ® C 18 Gravity, featuring a C 18 Gravity phase based on high purity NUCLEODUR ® silica gel. This high density C 18 phase, endcapped to suppress unwanted polar interactions, is particularly suitable for separating basic and other ionizable analytes. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it an ideal choice for method development and valuable for RP applications. With a particle size of 5 μm, this preparative separation column offers a pressure stability of 400 bar and temperature stability up to 60 °C. It's recommended for various applications, including anti-inflammatory drugs, herbicides, and immunosuppressants, among others.

• Category: Separation columns for HPLC
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Separation principle: Reversed phase (RP)
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Column shape: Preparative separation column
• Column type: HPLC column
• L x Ø internal (column): 50 x 10 mm
• Pore volume: 0.9 ml/g
• Column volume: 3.9 ml
• USP listing: L1
• Pressure stability: 400 bar
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Temperature stability: 60 ° C
• Endcapped: yes
• Particle type: Fully porous particles (FPP)
• Specific surface according to BET: 340 m²/g
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Phase: C 18 Gravity
• Pore size: 110 Å
• pH stability: 1,0-11,0
• Particle size: 5 µm