HPLC column NUCLEODUR ® C 18 Gravity SB, 3 µm, 50 mm, 4.6 mm

Designed with efficiency in synthetic processes in mind, this HPLC column features a C 18 Gravity SB phase, endcapped for improved performance under highly aqueous conditions. With a particle size of 3 μm, it offers a pressure stability of 600 bar and temperature stability up to 60°C. The column's specific surface area of 340 m²/g ensures optimal interaction and retention mechanisms, particularly hydrophobic (van der Waals) with additional polar interactions. Suitable for overall sophisticated analytical separations, this column excels in applications such as antibiotics, organic acids, water-soluble vitamins, and method development, making it an ideal choice for separating polar compounds.

• Category: Separation columns for HPLC
• Column type: HPLC column
• USP listing: L1
• L x Ø internal (column): 50 x 4.6 mm
• Interactions / retention mechanism: hydrophobic (van der Waals) with additional polar interactions
• Column volume: 0.83 ml
• Pore volume: 0.9 ml/g
• Eluent in column: Acetonitrile - Water
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column
• Phase: C 18 Gravity SB
• Similar phases: NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS
• Surface chemistry: Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification
• Temperature stability: 60 ° C
• pH stability: 1,0-9,0
• Particle size: 3 µm
• Recommended application(s): Overall sophisticated analytical separations Antibiotics Organic acids Ideal for method development Especially for polar compounds Water soluble vitamins Excellent performance under highly aqueous conditions
• Specific surface according to BET: 340 m²/g
• Pressure stability: 600 bar
• Pore size: 110 Å
• Particle type: Fully porous particles (FPP)
• Endcapped: yes