HPLC column NUCLEODUR ® C 18 Pyramid, 5 µm, 100 mm, 4 mm

Formulated to support synthetic operations, the Hplc Column Nucleodur® C 18 Pyramid, 5 μm, 100 mm, 4 mm offers a reversed phase separation principle ideal for very polar compounds such as pharmaceutical raw materials, analgesics, and water-soluble vitamins. Its particle size of 5 μm ensures optimal pressure stability up to 600 bar, while its temperature stability extends to 60°C. This fully porous particle (FPP) column features octadecyl (C 18, ODS) modification with polar endcapping, making it suitable for aqueous eluents and offering hydrophobic and polar interactions through hydrogen bonding. The column's specific surface area of 340 m²/g allows for efficient separations, and its pH stability ranges from 1.0

• Category: Separation columns for HPLC
• Eluent in column: Acetonitrile - Water
• Column shape: Analytical separation column
• Endcapped: yes
• L x Ø internal (column): 100 x 4 mm
• Column volume: 1.25 ml
• Column type: HPLC column
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Pressure stability: 600 bar
• Particle size: 5 µm
• Particle type: Fully porous particles (FPP)
• Phase: C 18 Pyramid
• Temperature stability: 60 ° C
• Specific surface according to BET: 340 m²/g
• Separation principle: Reversed phase (RP)
• Pore size: 110 Å
• USP listing: L1
• pH stability: 1,0-9,0
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Pore volume: 0.9 ml/g