A reliable solution for controlled synthesis, the Hplc Column Nucleodur ® C 18 Pyramid offers exceptional performance in the separation of various pharmaceutical raw materials, including very polar compounds such as analgesics, water-soluble vitamins, complexing agents, nucleic acid bases, organic acids, penicillin antibiotics, and more. With a particle size of 5 μm and a specific surface area of 340 m²/g according to BET, this fully porous particle (FPP) column provides high efficiency and resolution. Its octadecyl (C 18 , ODS) modification with polar endcapping allows it to handle aqueous eluents effectively, making it ideal for applications requiring 100% aqueous eluents. This HPLc column's recommended operating temperature range is between 60°

• Category: Separation columns for HPLC
• Particle size: 5 µm
• Pore volume: 0.9 ml/g
• Particle type: Fully porous particles (FPP)
• Application Database (Macherey-Nagel): HPLC SPE
• Pore size: 110 Å
• pH stability: 1,0-9,0
• Specific surface according to BET: 340 m²/g
• Pressure stability: 600 bar
• Temperature stability: 60 ° C
• Phase: C 18 Pyramid
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Column volume: 1.75 ml
• L x Ø internal (column): 250 x 3 mm
• Column type: HPLC column
• USP listing: L1
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column