Designed for professional use, the HPLC Column Nucleoshell® PFP, 100 mm, 4.6 mm offers exceptional performance in the separation of aromatic and unsaturated compounds, halogenated hydrocarbons, high retention of basic compounds, isomers, phenols, pharmaceutical products, and polar compounds. Its unique pentafluorophenylpropyl (PFP) modification on core-shell, superficially porous particles (SPP) provides an alternative selectivity compared to traditional C18 modifications. With a specific surface area of 90 m²/g, this reversed-phase (RP) column also exhibits excellent compatibility with LC/MS applications due to its low bleeding characteristics. It operates under a pressure of up to 600 bar and maintains stability at temperatures up to 60°C.

• Category: Separation columns for HPLC
• Particle type: Core-shell, superficially porous particles (SPP)
• Separation principle: Reversed phase (RP)
• L x Ø internal (column): 100 x 4.6 mm
• Pressure stability: 600 bar
• USP listing: L43
• Application Database (Macherey-Nagel): HPLC
• Particle size: 2.7 µm
• Column type: HPLC column
• Eluent in column: Acetonitrile - Water
• Pore volume: 0.9 ml/g
• pH stability: 1,0-9,0
• Column volume: 1.65 ml
• Endcapped: yes
• Pore size: 90 Å
• Interactions / retention mechanism: polar (H bond), dipole-dipole, π-π and hydrophobic
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Specific surface according to BET: 90 m²/g
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Halogenated hydrocarbons High retention of basic compounds Isomers Phenols Pharmaceutical products Especially for polar compounds Suitable for LC-MS
• Temperature stability: 60 ° C
• Column shape: Analytical separation column
• Phase: PFP