A reliable solution for controlled synthesis, the Hplc Column Nucleodur ® PFP, 3 μm, 50 mm, 3 mm, falls under the category of Separation columns for HPLC. Featuring a Pentafluorophenylpropyl (PFP) modification on high purity NUCLEODUR ® silica gel, this hydrophobic phase offers an alternative selectivity compared to traditional C 18 modifications. Its four retention mechanisms—polar interactions (H bonds), dipole-dipole interactions, π-π interactions, and hydrophobic interactions—make it suitable for LC/MS applications due to its low bleeding characteristics. With a recommended application range including antibiotics, aromatic and unsaturated compounds, basic compounds, halogenated compounds, isomers, pharmaceutical products, phenols, and

• Category: Separation columns for HPLC
• USP listing: L43
• L x Ø internal (column): 50 x 3 mm
• Pressure stability: 600 bar
• Particle type: Fully porous particles (FPP)
• Specific surface according to BET: 340 m²/g
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Basic compounds Suitable for LC-MS Halogenated compounds Isomers Pharmaceutical products Phenols Especially for polar compounds
• Endcapped: yes
• Application Database (Macherey-Nagel): HPLC
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Column volume: 0.35 ml
• Particle size: 3 µm
• Column type: HPLC column
• Pore volume: 0.9 ml/g
• Eluent in column: Acetonitrile - Water
• Column shape: Analytical separation column
• Phase: PFP
• pH stability: 1,0-9,0
• Temperature stability: 60 ° C
• Pore size: 110 Å
• Interactions / retention mechanism: polar (H-bond), dipole-dipole, π-π and hydrophobic
• Separation principle: Reversed phase (RP)