HPLC column NUCLEODUR ® C 18 Pyramid, 250 mm, 21 mm

Crafted to support technical production environments, the HPLC Column Nucleodur® C 18 Pyramid, measuring 250mm in length and 21mm in diameter, offers a versatile solution for separating complex mixtures. This preparative separation column features fully porous particles (FPP), a particle size of 5μm, and a specific surface area of 340m²/g, ensuring efficient and reliable performance. Its unique octadecyl (C 18 , ODS) modification with polar endcapping allows it to handle very polar compounds, making it ideal for applications such as pharmaceutical raw materials, organic acids, penicillin antibiotics, and water-soluble vitamins. With a pressure stability of up to 400bar and temperature stability at 60°C, this column delivers robust results under demanding conditions.

• Category: Separation columns for HPLC
• Pore size: 110 Å
• Phase: C 18 Pyramid
• Column shape: Preparative separation column
• Endcapped: yes
• Separation principle: Reversed phase (RP)
• Temperature stability: 60 ° C
• Column type: HPLC column
• Particle type: Fully porous particles (FPP)
• Specific surface according to BET: 340 m²/g
• Pressure stability: 400 bar
• USP listing: L1
• Eluent in column: Acetonitrile - Water
• L x Ø internal (column): 250 x 21 mm
• Surface chemistry: Octadecyl (C 18 , ODS) modification, Polar endcapping
• Pore volume: 0.9 ml/g
• Interactions / retention mechanism: hydrophobic and polar (H bonds)
• pH stability: 1,0-9,0
• Recommended application(s): Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics
• Similar phases: Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A
• Column volume: 87 ml
• Particle size: 5 µm