Built to deliver predictable results in synthesis routines, this Separation column for HPLC, specifically the HPLC column NUCLEODUR ® C 18 Isis, boasts a nonpolar crosslinked polymeric octadecyl (C 18 , ODS) modification that provides high steric selectivity. With a particle size of 3 µm and a pressure stability of 600 bar, it offers exceptional performance in separating positional and structural isomers, planar/non-planar molecules, steroids, and even fat-soluble vitamins. Its recommended application also includes LC-MS for (o,p,m-)substituted aromatics. This column's unique properties make it an ideal choice for various analytical applications due to its interactions via both steric and hydrophobic mechanisms.

• Category: Separation columns for HPLC
• Eluent in column: Acetonitrile - Water
• Column type: HPLC column
• Temperature stability: 60 ° C
• L x Ø internal (column): 100 x 4 mm
• Specific surface according to BET: 340 m²/g
• Particle size: 3 µm
• Particle type: Fully porous particles (FPP)
• Phase: C 18 Isis
• Interactions / retention mechanism: steric and hydrophobic
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• pH stability: 1,0-10,0
• Pore size: 110 Å
• Surface chemistry: Nonpolar crosslinked polymeric octadecyl (C 18 , ODS) modification, High steric selectivity
• Recommended application(s): Separation of positional and structural isomers Planar/non-planar molecules Steroids Suitable for LC-MS (o,p,m-)Substituted aromatics Fat-soluble vitamins Exceptional steric selectivity
• Separation principle: Reversed phase (RP)
• Column shape: Analytical separation column
• Column volume: 1.25 ml
• Endcapped: yes
• USP listing: L1