Optimized for controlled laboratory processes, the Separation columns for HPLC category includes the HPLC column NUCLEODUR® C 8 Gravity, 5 μm, 250 mm, 4.6 mm. This analytical separation column features a high density C 8 phase based on high purity NUCLEODUR® silica gel, endcapped to suppress unwanted polar interactions. Its enhanced pH stability, LC/MS suitability, and superior base deactivation make it ideal for method development and valuable for RP applications. With a specific surface area of 340 m²/g, this column offers excellent performance for separating basic and other ionizable analytes, including pharmaceuticals, antidepressants, and immunosuppressants. It operates under pressure up to 600 bar and maintains temperature stability up to 60°C. The recommended

• Category: Separation columns for HPLC
• Endcapped: yes
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Temperature stability: 60 ° C
• Pore volume: 0.9 ml/g
• Particle type: Fully porous particles (FPP)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Column volume: 4.15 ml
• Separation principle: Reversed phase (RP)
• L x Ø internal (column): 250 x 4.6 mm
• Column type: HPLC column
• Eluent in column: Acetonitrile - Water
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification
• Application Database (Macherey-Nagel): HPLC
• USP listing: L7
• Particle size: 5 µm
• Phase: C 8 Gravity
• Pore size: 110 Å
• Column shape: Analytical separation column
• Specific surface according to BET: 340 m²/g
• Pressure stability: 600 bar
• pH stability: 1,0-11,0