Adapted for use across diverse chemical handling environments, the HPLC column NUCLEODUR® PFP offers a versatile solution for separating aromatic and unsaturated compounds, basic compounds, halogenated compounds, isomers, pharmaceutical products, phenols, and especially polar compounds. Based on high purity NUCLEODUR® silica gel, this reversed-phase column features a pentafluorophenylpropyl (PFP) modification that provides an alternative selectivity compared to traditional C18 modifications. Its unique separation mechanism encompasses polar interactions (H bonds), dipole-dipole interactions, π-π interactions, and hydrophobic interactions, making it suitable for LC/MS applications due to its low bleeding characteristics. With a particle size of 5 μm, pressure stability up to 600 bar, temperature stability at 60

• Category: Separation columns for HPLC
• Eluent in column: Acetonitrile - Water
• Column type: HPLC column
• Pressure stability: 600 bar
• Pore volume: 0.9 ml/g
• Application Database (Macherey-Nagel): HPLC
• Column shape: Analytical separation column
• USP listing: L43
• Recommended application(s): Antibiotics Aromatic and unsaturated compounds Basic compounds Suitable for LC-MS Halogenated compounds Isomers Pharmaceutical products Phenols Especially for polar compounds
• Specific surface according to BET: 340 m²/g
• Particle type: Fully porous particles (FPP)
• L x Ø internal (column): 100 x 4.6 mm
• Surface chemistry: Pentafluorophenylpropyl (PFP) modification
• Interactions / retention mechanism: polar (H-bond), dipole-dipole, π-π and hydrophobic
• Temperature stability: 60 ° C
• Endcapped: yes
• Particle size: 5 µm
• Column volume: 1.65 ml
• pH stability: 1,0-9,0
• Separation principle: Reversed phase (RP)
• Pore size: 110 Å
• Phase: PFP