Intended for structured formulation workflows, the HPLC column Nucleodur® C 18 ec offers a versatile solution for various applications within liquid chromatography. This analytical separation column features a particle size of 3 μm, a column volume of 2.5 ml, and a length of 150 mm by an inner diameter of 4.6 mm. Its medium density monomeric octadecyl (C 18, ODS) modification provides excellent separation capabilities for a broad range of analytes, including basic, neutral, or acidic drugs, derivatized amino acids, pesticides, fat-soluble vitamins, aldehydes, ketones, and phenolic compounds. With a specific surface area of 340 m²/g, this column ensures efficient interaction and retention mechanisms through hydrophobic van der Waals interactions

• Category: Separation columns for HPLC
• Recommended application(s): Routine analyses Aldehydes Basic, neutral or acidic drugs Derivatised amino acids Fat-soluble vitamins Ketones Pesticides Phenolic compounds
• Column shape: Analytical separation column
• Specific surface according to BET: 340 m²/g
• Endcapped: yes
• Surface chemistry: Medium density monomeric octadecyl (C 18 , ODS) modification
• Column type: HPLC column
• Particle type: Fully porous particles (FPP)
• Column volume: 2.5 ml
• Separation principle: Reversed phase (RP)
• Temperature stability: 60 ° C
• Pressure stability: 600 bar
• Similar phases: NUCLEOSIL ® C 18 Spherisorb ® ODS II Symmetry ® C 18 Hypersil™ ODS Inertsil ® ODS II Kromasil ® C 18 LiChrospher ® RP 18
• pH stability: 1,0-9,0
• Application Database (Macherey-Nagel): HPLC
• L x Ø internal (column): 150 x 4.6 mm
• Interactions / retention mechanism: hydrophobic (van der Waals interactions), some residual silanol interactions
• Eluent in column: Acetonitrile - Water
• Particle size: 3 µm
• Pore volume: 0.9 ml/g
• USP listing: L1
• Phase: C 18 ec
• Pore size: 110 Å