Widely applied in chemical workflows, separation columns for HPLC play an essential role in the analysis of various substances. One such column is the HPLC column NUCLEODUR® C 8 Gravity, featuring a 3 μm particle size, 75 mm length, and 4.6 mm diameter. This column's C 8 Gravity phase, based on high purity NUCLEODUR® silica gel, offers excellent pH stability, LC/MS suitability, and superior base deactivation, making it ideal for method development and RP applications. Its unique endcapping design suppresses unwanted polar interactions, ensuring optimal performance for the separation of basic and other ionizable analytes. With a specific surface area of 340 m²/g and a temperature stability of up to 60°C, this column is versatile and reliable for a wide range of applications

• Category: Separation columns for HPLC
• Pressure stability: 600 bar
• Interactions / retention mechanism: hydrophobic (van der Waals)
• Similar phases: NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8
• Specific surface according to BET: 340 m²/g
• pH stability: 1,0-11,0
• Column type: HPLC column
• L x Ø internal (column): 75 x 4.6 mm
• Column shape: Analytical separation column
• Eluent in column: Acetonitrile - Water
• Separation principle: Reversed phase (RP)
• Particle type: Fully porous particles (FPP)
• Endcapped: yes
• Pore volume: 0.9 ml/g
• USP listing: L7
• Phase: C 8 Gravity
• Column volume: 1.25 ml
• Particle size: 3 µm
• Pore size: 110 Å
• Recommended application(s): In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals
• Temperature stability: 60 ° C
• Surface chemistry: Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification