Manufactured to meet research and production requirements, this HPLC column Nucleodur® C 18 ec is designed for routine analyses and upscaling for preparative HPLC. With a particle size of 3 μm and a pore size of 110 Å, it offers a wide range of applications, including the separation of basic, neutral, or acidic drugs, derivatized amino acids, pesticides, fat-soluble vitamins, aldehydes, ketones, and phenolic compounds. This column's surface chemistry features medium density monomeric octadecyl (C 18, ODS) modification, ensuring hydrophobic interactions and some residual silanol interactions. The column's specific surface area, as per BET, is 340 m²/g, providing excellent separation efficiency.

• Category: Separation columns for HPLC
• Pressure stability: 600 bar
• L x Ø internal (column): 250 x 4.6 mm
• Surface chemistry: Medium density monomeric octadecyl (C 18 , ODS) modification
• Recommended application(s): Routine analyses Aldehydes Basic, neutral or acidic drugs Derivatised amino acids Fat-soluble vitamins Ketones Pesticides Phenolic compounds
• Separation principle: Reversed phase (RP)
• Column volume: 4.15 ml
• Particle size: 3 µm
• Pore size: 110 Å
• Particle type: Fully porous particles (FPP)
• Column shape: Analytical separation column
• Application Database (Macherey-Nagel): HPLC
• Phase: C 18 ec
• Endcapped: yes
• Similar phases: NUCLEOSIL ® C 18 Spherisorb ® ODS II Symmetry ® C 18 Hypersil™ ODS Inertsil ® ODS II Kromasil ® C 18 LiChrospher ® RP 18
• USP listing: L1
• Temperature stability: 60 ° C
• Eluent in column: Acetonitrile - Water
• Pore volume: 0.9 ml/g
• Specific surface according to BET: 340 m²/g
• Interactions / retention mechanism: hydrophobic (van der Waals interactions), some residual silanol interactions
• pH stability: 1,0-9,0
• Column type: HPLC column