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<p>Produced for stability across temperature-sensitive applications, the Separation columns for HPLC, specifically the Hplc Column Nucleodur ® Polartec, 5 μm, 250 Mm, 2 Mm, exhibit exceptional performance under high aqueous conditions. With a pore size of 110 Å and a particle size of 5 μm, these fully porous particles (FPP) offer a specific surface area of 340 m²/g, ensuring optimal interaction between analytes and the octadecyl phase (C 18 , ODS) modification, which includes an embedded polar group (PEG). This unique combination results in a hydrophobic phase with pronounced hydrophilic properties, making it suitable for reversed phase (RP) separations and LC/MS applications due to its low bleeding characteristics. The column's recommended applications include amino ac</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic and polar (H bonds)</li> <li><strong>USP listing:</strong> L1 L60</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Surface chemistry:</strong> Octadecyl phase (C 18 , ODS) modification, with embedded polar group (PEG)</li> <li><strong>Recommended application(s):</strong> Amino acids Basic pharmaceuticals Especially for polar compounds Nitrogen containing compounds Organic acids Pesticides Phenols Suitable for 100 % aqueous eluents Suitable for LC-MS Water-soluble vitamins</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Column volume:</strong> 0.8 ml</li> <li><strong>Particle size:</strong> 5 µm</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>pH stability:</strong> 1,0-9,0</li> <li><strong>L x Ø internal (column):</strong> 250 x 2 mm</li> <li><strong>Phase:</strong> PolarTec</li> </ul>
Product Detail
<p>Manufactured to meet research and production requirements, this HPLC column Nucleodur® C 8 ec features a particle size of 3 μm and an internal length of 125 mm x 4 mm. It boasts a medium density monomeric octyl (C 8 , MOS) modification as its surface chemistry, making it suitable for routine analyses of aldehydes, basic, neutral, or acidic drugs, derivatized amino acids, fat-soluble vitamins, ketones, pesticides, and phenolic compounds. With a specific surface area of 340 m²/g according to BET, this column offers excellent separation capabilities while maintaining pressure stability up to 600 bar and temperature stability at 60° C. Its recommended eluent is acetonitrile-water, and it exhibits hydrophobic (van der Wa</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>USP listing:</strong> L7</li> <li><strong>Surface chemistry:</strong> Medium density monomeric octyl (C 8 , MOS) modification</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic (van der Waals interactions), some residual silanol interactions</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Recommended application(s):</strong> Routine analyses Aldehydes Basic, neutral or acidic drugs Derivatised amino acids Fat-soluble vitamins Ketones Pesticides Phenolic compounds</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>pH stability:</strong> 1,0-9,0</li> <li><strong>L x Ø internal (column):</strong> 125 x 4 mm</li> <li><strong>Particle size:</strong> 3 µm</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Column volume:</strong> 1.56 ml</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Similar phases:</strong> NUCLEOSIL ® C 8 NUCLEOSIL ® C 8 ec Spherisorb ® C 8 Symmetry ® C 8 Hypersil™ MOS Kromasil ® C 8 LiChrospher ® RP 8</li> <li><strong>Phase:</strong> C 8 ec</li> </ul>
Product Detail
<p>Engineered to maintain reliability in process-driven workflows, the HPLC column NUCLEODUR® C 8 Gravity, 5 μm, 250 mm, 2 mm offers exceptional performance for reversed phase separations. Its base deactivated (BDS) surface chemistry, combined with a high density C 8 phase, ensures minimal unwanted polar interactions, making it ideal for the separation of basic and ionizable analytes. With a pH stability range of 1.0-11.0, this column is an excellent choice for method development and RP applications, especially those involving extreme pH values. Furthermore, its pressure stability up to 600 bar and temperature stability up to 60°C ensure robustness in various conditions.</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>pH stability:</strong> 1,0-11,0</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Column volume:</strong> 0.8 ml</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Recommended application(s):</strong> In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Particle size:</strong> 5 µm</li> <li><strong>L x Ø internal (column):</strong> 250 x 2 mm</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Surface chemistry:</strong> Base deactivated (BDS), High density monomeric octyl (C 8 , MOS) modification</li> <li><strong>USP listing:</strong> L7</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic (van der Waals)</li> <li><strong>Similar phases:</strong> NUCLEOSIL ® C 8 HD Xterra ® RP 8 / MS C 8 Luna ® C 8 Zorbax ® Eclipse XDB-C 8</li> <li><strong>Phase:</strong> C 8 Gravity</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> </ul>
Product Detail
<p>Developed to align with modern chemical standards, the Hplc Column Nucleodur ® C 18 Pyramid, 3 μm, 150 mm, 3 mm features a C 18 Pyramid phase with polar endcapping, making it suitable for aqueous eluents. This analytical separation column boasts a specific surface area of 340 m²/g and a pore size of 110 Å, ensuring efficient separation of various compounds such as pharmaceutical raw materials, very polar compounds, analgesics, and water-soluble vitamins. With a pressure stability of 600 bar and temperature stability up to 60°C, this column is designed to handle demanding conditions while maintaining its integrity. The column's particle size of 3 μm and fully porous particles (FPP) contribute to its high efficiency</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Surface chemistry:</strong> Octadecyl (C 18 , ODS) modification, Polar endcapping</li> <li><strong>Particle size:</strong> 3 µm</li> <li><strong>L x Ø internal (column):</strong> 150 x 3 mm</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Recommended application(s):</strong> Pharmaceutical raw materials Very polar compounds Analgesics Suitable for 100 % aqueous eluents Water-soluble vitamins Complexing agents Nucleic acid bases Organic acids Penicillin antibiotics</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Phase:</strong> C 18 Pyramid</li> <li><strong>USP listing:</strong> L1</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Column volume:</strong> 1.05 ml</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic and polar (H bonds)</li> <li><strong>Similar phases:</strong> Aqua ® Synergi™ Hydro-RP AQ Atlantis ® dC 18 Polaris ® C18-A</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>pH stability:</strong> 1,0-9,0</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> </ul>
Product Detail
<p>Prepared for use in regulated laboratory conditions, the HPLC column NUCLEODUR ® C 18 Gravity, featuring a 3 μm particle size and a 250 mm length, is a versatile tool within the category of separation columns for HPLC. Its high density C 18 phase, based on high purity NUCLEODUR ® silica gel, offers excellent pH stability ranging from 1 to 11, making it ideal for separating basic and other ionizable analytes. Endcapped to suppress unwanted polar interactions, this column is particularly suited for reversed phase (RP) applications, including method development. With a specific surface area of 340 m²/g and a pressure stability of up to 600 bar, it delivers reliable results under various conditions.</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Column volume:</strong> 4.15 ml</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>pH stability:</strong> 1,0-11,0</li> <li><strong>Similar phases:</strong> NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS</li> <li><strong>Recommended application(s):</strong> In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Surface chemistry:</strong> Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification</li> <li><strong>L x Ø internal (column):</strong> 250 x 4.6 mm</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic (van der Waals)</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Particle size:</strong> 3 µm</li> <li><strong>USP listing:</strong> L1</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Phase:</strong> C 18 Gravity</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> </ul>
Product Detail
<p>Developed for demanding processing applications, the HPLC column NUCLEOSHELL ® PFP, 150 MM, 3 MM, falls under the category of separation columns for HPLC. Featuring a pentafluorophenylpropyl (PFP) modification on its core-shell, superficially porous particles (SPP), this hydrophobic phase offers an alternative selectivity compared to traditional C18 modifications. Its unique structure allows for separation based on four retention mechanisms: polar interactions (H bonds), dipole-dipole interactions, π-π interactions, and hydrophobic interactions. Additionally, it exhibits low bleeding characteristics, making it suitable for LC/MS. With a particle size of 2.7 μm and a pressure stability of 600 bar, this analytical separation column is ideal for separating aromatic and unsatur</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Particle size:</strong> 2.7 µm</li> <li><strong>USP listing:</strong> L43</li> <li><strong>Specific surface according to BET:</strong> 90 m²/g</li> <li><strong>Interactions / retention mechanism:</strong> polar (H bond), dipole-dipole, π-π and hydrophobic</li> <li><strong>Phase:</strong> PFP</li> <li><strong>Column volume:</strong> 1.05 ml</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>L x Ø internal (column):</strong> 150 x 3 mm</li> <li><strong>pH stability:</strong> 1,0-9,0</li> <li><strong>Pore size:</strong> 90 Å</li> <li><strong>Recommended application(s):</strong> Antibiotics Aromatic and unsaturated compounds Halogenated hydrocarbons High retention of basic compounds Isomers Phenols Pharmaceutical products Especially for polar compounds Suitable for LC-MS</li> <li><strong>Surface chemistry:</strong> Pentafluorophenylpropyl (PFP) modification</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Particle type:</strong> Core-shell, superficially porous particles (SPP)</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Column shape:</strong> Analytical separation column</li> </ul>
Product Detail
<p>Engineered for consistent performance, the Hplc Column Nucleodur® Phenyl-Hexyl, 3 μm, 250 mm, 4.6 mm, is designed for reversed phase separations, particularly suited for polar compounds such as antibiotics, aromatic and unsaturated compounds, pharmaceutical products, steroids, and applications requiring LC-MS compatibility. This analytical separation column features fully porous particles (FPP), a pore size of 110 Å, and a specific surface area of 340 m²/g, ensuring optimal efficiency and reproducibility. Its unique phenylhexyl surface chemistry facilitates both π-π interactions and hydrophobic interactions, making it an ideal choice for a wide range of applications.</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Particle size:</strong> 3 µm</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Interactions / retention mechanism:</strong> π-π and hydrophobic</li> <li><strong>USP listing:</strong> L11</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Surface chemistry:</strong> Phenylhexyl modification</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Phase:</strong> Phenyl-Hexyl</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>pH stability:</strong> 1,0-10,0</li> <li><strong>Recommended application(s):</strong> Antibiotics Aromatic and unsaturated compounds Suitable for LC-MS Pharmaceutical products Especially for polar compounds Steroids</li> <li><strong>L x Ø internal (column):</strong> 250 x 4.6 mm</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Column volume:</strong> 4.15 ml</li> </ul>
Product Detail
<p>Suitable for laboratory and industrial environments, the Separation columns for HPLC category includes the Hplc Column Nucleodur ® C 18 Htec, 5 µm, 100 mm, 50 mm. This particular column features a reversed phase (RP) separation principle, a base deactivated (BDS), high density octadecyl (C 18 , ODS) modification, and a surface chemistry that allows for hydrophobic (van der Waals) interactions. It boasts a specific surface area of 340 m²/g, as well as a particle size of 5 µm and a pressure stability of 400 bar. With a recommended application range including aldehydes, fat-soluble vitamins, and phenolic compounds, this column is an ideal choice for various industries requiring high loading capacity and versatile separ</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Recommended application(s):</strong> Aldehydes Applications at extreme pH values (1-11) Alkaline, neutral and acidic pharmaceuticals Derivatised amino acids Fat-soluble vitamins Suitable for LC-MS High loading capacity Ketones Pesticides Phenolic compounds</li> <li><strong>Particle size:</strong> 5 µm</li> <li><strong>Phase:</strong> C 18 HTec</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic (van der Waals)</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>L x Ø internal (column):</strong> 100 x 50 mm</li> <li><strong>Column volume:</strong> 196 ml</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Column shape:</strong> Preparative separation column</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>Pressure stability:</strong> 400 bar</li> <li><strong>Surface chemistry:</strong> Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification</li> <li><strong>USP listing:</strong> L1</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>pH stability:</strong> 1,0-11,0</li> </ul>
Product Detail
<p>Built to deliver predictable results in synthesis routines, the HPLC Column Nucleodur® Phenyl-Hexyl, 3 μm, 100 mm, 3 mm offers exceptional performance as a reversed-phase (RP) separation tool. Featuring fully porous particles (FPP), this analytical separation column boasts a specific surface area of 340 m²/g, ensuring optimal interaction between analytes and the stationary phase. With a pore size of 110 Å and a pore volume of 0.9 ml/g, it accommodates a wide range of eluents, including acetonitrile-water mixtures. Its unique phenylhexyl surface chemistry supports both π-π interactions and hydrophobic interactions, making it particularly effective for separating aromatic and unsaturated compounds, antibiotics, pharmaceutical products, ster</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Application Database (Macherey-Nagel):</strong> HPLC</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>USP listing:</strong> L11</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Column volume:</strong> 0.7 ml</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>L x Ø internal (column):</strong> 100 x 3 mm</li> <li><strong>Phase:</strong> Phenyl-Hexyl</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Recommended application(s):</strong> Antibiotics Aromatic and unsaturated compounds Suitable for LC-MS Pharmaceutical products Especially for polar compounds Steroids</li> <li><strong>Particle size:</strong> 3 µm</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>pH stability:</strong> 1,0-10,0</li> <li><strong>Interactions / retention mechanism:</strong> π-π and hydrophobic</li> <li><strong>Surface chemistry:</strong> Phenylhexyl modification</li> </ul>
Product Detail
<p>Suitable for laboratory and industrial environments, the Hplc Column Nucleodur ® NH 2 -RP, 5 μm, 250 mm, 2 mm features a particle size of 5 μm and a specific surface area of 340 m²/g according to BET. This analytical separation column is endcapped and offers a pore size of 110 Å, a pore volume of 0.9 ml/g, and a pressure stability of up to 600 bar. It is suitable for separating polar compounds under reversed phase (RP) conditions, such as sugars and DNA bases, as well as hydrocarbons under normal phase (NP) conditions. With a temperature stability of 60°C, this column is ideal for various applications within the field of liquid chromatography (LC, HPLC).</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Interactions / retention mechanism:</strong> polar/ionic and hydrophobic</li> <li><strong>pH stability:</strong> 2,0-8,0</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Phase:</strong> NH 2 -RP</li> <li><strong>L x Ø internal (column):</strong> 250 x 2 mm</li> <li><strong>Surface chemistry:</strong> Aminopropyl (NH 2 ) modification</li> <li><strong>Particle size:</strong> 5 µm</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Column volume:</strong> 0.8 ml</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Recommended application(s):</strong> Polar compounds under RP conditions (sugars, DNA bases) Hydrocarbons under NP conditions</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Similar phases:</strong> NUCLEOSIL ® NH 2 / NH 2 -RP</li> <li><strong>USP listing:</strong> L8</li> <li><strong>Endcapped:</strong> no</li> <li><strong>Separation principle:</strong> Multi-mode (NP and RP), Reversed phase (RP)</li> </ul>
Product Detail
<p>Configured for stable performance in synthesis settings, this HPLC column from Macherey-Nagel features a HILIC phase, ammonium – sulfonic acid (zwitterionic) modification, and a particle size of 1.8 μm. With a pore size of 110 Å, it offers a specific surface area of 340 m²/g and a pore volume of 0.9 ml/g. This UHPLC column is suitable for a wide range of applications, including the separation of highly polar analytes such as amino acids, peptides, and water-soluble vitamins. Its pressure stability of 900 bar and temperature stability up to 60°C ensure reliable operation even under demanding conditions. This analytical separation column, delivered with an instruction leaflet and certificate of analysis, is ideal for those seeking efficient HPLC separ</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Column volume:</strong> 0.3 ml</li> <li><strong>Particle size:</strong> 1.8 µm</li> <li><strong>Endcapped:</strong> no</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Surface chemistry:</strong> Ammonium – sulfonic acid (zwitterionic) modification</li> <li><strong>Recommended application(s):</strong> Amino acids HILIC applications Highly polar analytes Hydrophilic compounds Nucleosides Oligonucleotides Organic polar acids and bases Peptides Polar natural products Water-soluble vitamins</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>L x Ø internal (column):</strong> 100 x 2 mm</li> <li><strong>pH stability:</strong> 2,0-8,5</li> <li><strong>Phase:</strong> HILIC</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Pressure stability:</strong> 900 bar</li> <li><strong>Separation principle:</strong> Hydrophilic Interaction Chromatography (HILIC)</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>Interactions / retention mechanism:</strong> ionic / hydrophilic and electrostatic</li> <li><strong>Application Database (Macherey-Nagel):</strong> HPLC</li> <li><strong>Column type:</strong> UHPLC column</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>USP listing:</strong> Not available or proprietary</li> <li><strong>Pore size:</strong> 110 Å</li> </ul>
Product Detail
<p>Built to deliver predictable results in synthesis routines, the HPLC column NUCLEODUR ® C 18 Gravity offers a high-density C 18 phase based on high-purity NUCLEODUR ® silica gel. Its endcapping feature minimizes unwanted polar interactions, making it ideal for separating basic and other ionizable analytes. With enhanced pH stability, LC/MS compatibility, and superior base deactivation, this column is an excellent choice for method development and valuable for RP applications. It features a particle size of 5 μm, a specific surface area of 340 m²/g, and a recommended application range that includes pharmaceuticals, pesticides, and herbicides.</p> <ul> <li><strong>Category:</strong> Separation columns for HPLC</li> <li><strong>Particle type:</strong> Fully porous particles (FPP)</li> <li><strong>Interactions / retention mechanism:</strong> hydrophobic (van der Waals)</li> <li><strong>Recommended application(s):</strong> In general compounds with ionizable functional groups such as basic pharmaceuticals and pesticides Analgesics Antidepressants Applications for extreme pH values (1-11) Anti-inflammatory drugs Herbicides Ideal for method development Immunosuppressants Pharmaceutical products Phytopharmaceuticals</li> <li><strong>Particle size:</strong> 5 µm</li> <li><strong>Separation principle:</strong> Reversed phase (RP)</li> <li><strong>Phase:</strong> C 18 Gravity</li> <li><strong>Column type:</strong> HPLC column</li> <li><strong>Similar phases:</strong> NUCLEOSIL ® C 18 HD Xterra ® RP 18 / MS C 18 Luna ® C 18 (2) Gemini ® Synergi™ Max RP Zorbax ® Extend C 18 Inertsil ® ODS III Purospher ® Star RP-18 Hypersil™ BDS</li> <li><strong>Pore size:</strong> 110 Å</li> <li><strong>Endcapped:</strong> yes</li> <li><strong>pH stability:</strong> 1,0-11,0</li> <li><strong>Surface chemistry:</strong> Base deactivated (BDS), High density octadecyl (C 18 , ODS) modification</li> <li><strong>Pore volume:</strong> 0.9 ml/g</li> <li><strong>L x Ø internal (column):</strong> 50 x 3 mm</li> <li><strong>Specific surface according to BET:</strong> 340 m²/g</li> <li><strong>Column volume:</strong> 0.35 ml</li> <li><strong>Temperature stability:</strong> 60 ° C</li> <li><strong>Column shape:</strong> Analytical separation column</li> <li><strong>Eluent in column:</strong> Acetonitrile - Water</li> <li><strong>Pressure stability:</strong> 600 bar</li> <li><strong>USP listing:</strong> L1</li> </ul>
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© 2023 Copyright. All Rights Reserved. Unit 19, Euroway House, Roydsdale Way, Bradford, BD4 6SE, UK
