Collagen type I, native, 10 g

Collagen is the most abundant protein in mammals and currently comprise 28 tissue-specific collagen types (Collagen Type I to XXVIII). They perform important structural, biomechanical, and organizational functions in tissues such as skin, bone, cartilage, and tendons. Furthermore, they support cell interactions and regulate processes such as cell growth, migration, and differentiation. Collagen type I, native CELLPURE ® >50%, Ultra Quality, low endotoxin, bovine, acid soluble This is acid-soluble, native Collagen Type I (Acid Soluble Collagen, ASC) derived from bovine hides sourced from BSE-safe countries in accordance with ISO 22442. Due to the gentle manufacturing process, the collagen is present as native, molecular telocollagen with preserved triple helix structure and intact N- and C-terminal telopeptides. The natural, intact structure ensures full biological activity of the collagen, including integrin-mediated cell adhesion as well as the ability to self-assemble into fibrillar collagen suprastructures. These biological properties make telocollagen an optimal biomaterial and an important foundation for tissue repair, regeneration, and biomedical research. Furthermore, it serves as a versatile building block for materials science. Collagen Type I is provided as a flake-like substrate (>50% collagen, <50% water) and is characterized by good solubility in slightly acidic as well as aqueous solutions, enabling simple and reproducible handling. The controlled manufacturing process ensures particularly high purity, characterized by very low endotoxin and total microbial count (TMC) levels. Properties: Native triple-helix structure Intact telopeptides (telocollagen) Full biological activity High biocompatibility Endotoxin-free Very good solubility Application: 3D cell culture Surface coating In vitro fibrillogenesis Tissue engineering Manufacture of bioinks Regenerative medicine Not a medical device / Not an IVD product